True QPI – Metrology of quantitative phase imaging systems for biomedical applications
Warsaw Univ. of Technology
Warsaw University of Technology
Warsaw University of Technology
PhotonHub Experience centre
English
6. 11. 2024
3 days
Polymer-based photonic components and large-area organic-photonics Laser-based Manufacturing Other
Manufacturing Health Other

The proposed Experience Centre is devoted to the metrological assessment of quantitative phase imaging (QPI) systems using bio-inspired phantoms manufactured via two-photon polymerization. The QPI is a rapidly growing 2D/3D microscopy market segment. An increasing number of companies deliver phase measurement systems worldwide. QPI systems are applied as efficient noninvasive (marker-free) measurement and monitoring tools in biomedical applications at the cellular level (e.g. in drug administration and interaction studies). However, there is no unified approach to metrology of QPI systems, making measurement validation and standardization challenging but also demanded by the market. For this reason, in True_QPI Experience Centre, participants will learn about the core advantages of QPI in biomedical imaging, how to setup metrological validation of their QPI instruments, how to use existing calibration objects to maximise their potential and how to design and use new, complex, bio-mimicking phantoms. Through these activities, the participants will gain insight into the limitations and uncertainty of phase measurements, which is vital for the QPI community and a unique opportunity for this industry to grow.
 

1)Gain knowledge and hands-on experience in 2D and 3D QPI methods
2)Design, manufacture and characterize calibration structures for 2D and 3D QPI
3)Learn how to evaluate quantitative phase measurement systems
4)Learn and recognize the limitations of the QPI tools and microfabrication methods

No experience
The course is ideally suited to the attendees from the two target groups: 1. Developers and manufacturers of phase microscopy products; 2. Laboratories and companies providing biomedical diagnostic services and farmaceutical companies introducing new medicines and utilize or plan to utilize QPI methods. It is desirable but not essential that course attendees have a basic understanding of photonics.
Advanced QPI instrumentation – holographic tomography system and an example of a measurement visualization
Advanced QPI instrumentation – holographic tomography system and an example of a measurement visualization
Fabrication facility – Photonic Professional GT 2 (Nanoscribe) two-photon polymerization printer
Fabrication facility – Photonic Professional GT 2 (Nanoscribe) two-photon polymerization printer
Phase microscopy calibration target fabricated with two-photon polymerization
Phase microscopy calibration target fabricated with two-photon polymerization
Mechatronics Faculty CeZaMat: Centre for Advanced Materials and Technologies
Warsaw
Poland
500 Euro
Includes catering and project consumables
3-9
Groups of 3x3 people per course
#Quantitative_Phase_Imaging#Biomedical_applications#DiDigital_holographic_microscopy#Optical_Diffraction_Tomography#3D_Refractive_Index#3D_nano_printing#Two-photon_Polymerization#Biology_inspired_phantoms#Metrology#QPI_Validation
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